Epilepsy; specially myoclonic & absence seizures • Panic Disorder • Convulsion • Anxiety Disorders

Dosage must be determined in each patient according to clinical response and tolerance. Seizure disorder Adults: Initial dose should not exceed 1.5 mg/day divided into three doses. Dosage may be increased in increments of 0.5 to 1 mg every three days until seizures are adequately controlled. Maintenance dosage must be individualized for each patient depending upon response. Maximum recommended daily dose is 20 mg. Children: The initial dose for infants and children (up to 10 years of age or 30 kg of body weight) should be between 0.01 and 0.03 mg/kg/day and should not exceed 0.05 mg/kg/day given in two or three divided doses. Dosage should be increased by not more than 0.25 to 0.5 mg every third day until a maintenance dose of 0.1 to 0.2 mg/kg of body weight has been reached, unless seizures are controlled. Panic disorder Adults: Initially 0.25 mg twice daily. Increased to 1 mg/day/in two divided doses after 3 days. Maximum dose 4 mg/day. Children: No clinical trial under 18 years of age.